HNRNPD antibody; AUF1 antibody; HNRPD antibody; Heterogeneous nuclear ribonucleoprotein D0 antibody; hnRNP D0 antibody; AU-rich element RNA-binding protein 1 antibody;
Product description
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.
Immunogen
The antiserum was produced against synthesized peptide derived from human hnRPD. AA range:49-98
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIHCIF
WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
HNRNPD antibody AUF1 antibody HNRPD antibody Heterogeneous nuclear ribonucleoprotein D0 antibody hnRNP D0 antibody AU-rich element RNA-binding protein 1 antibody