| Product Name |
HoxD10 |
| Antibody Type |
Primary Antibodies |
| Antigen Alias |
HOXD10 antibody; HOX4D antibody; HOX4E antibody; Homeobox protein Hox-D10 antibody; Homeobox protein Hox-4D antibody; Homeobox protein Hox-4E antibody; |
| Product description |
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease. |
| Immunogen |
The antiserum was produced against synthesized peptide derived from human HOXD10. AA range:291-340 |
