OM630264 WB.jpg" data-gallery-id="gallery2"
data-title="WB"
data-description="Expression results of key genes (a) related to the antibacterial mechanism of PSF, PSF/GO, and PSF/GO/Ag (0.7) fibrous membranes against S. aureus after 24 h of antibacterial treatment."
data-app="WB"
alt="WB"
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OM630264 WB.jpg" data-gallery-id="gallery1" loading="lazy" decoding="async" style="object-fit: contain;"
data-title="WB"
data-description="Expression results of key genes (a) related to the antibacterial mechanism of PSF, PSF/GO, and PSF/GO/Ag (0.7) fibrous membranes against S. aureus after 24 h of antibacterial treatment."
data-app="WB"
alt="WB">
Expression results of key genes (a) related to the antibacterial mechanism of PSF, PSF/GO, and PSF/GO/Ag (0.7) fibrous membranes against S. aureus after 24 h of antibacterial treatment.
Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Immunogen
The antiserum was produced against synthesized peptide derived from human DFFA. AA range:151-200
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IFIHCWB
WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
DFFA antibody DFF1 antibody DFF45 antibody H13 antibody DNA fragmentation factor subunit alpha antibody DNA fragmentation factor 45 kDa subunit antibody DFF-45 antibody Inhibitor of CAD antibody ICAD antibody
Expression results of key genes (a) related to the antibacterial mechanism of PSF, PSF/GO, and PSF/GO/Ag (0.7) fibrous membranes against S. aureus after 24 h of antibacterial treatment.