| Product Name | IgA |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IGHA1 antibody; Ig alpha-1 chain C region antibody; IGHA2 antibody; Ig alpha-2 chain C region antibody; |
| Product description | disease:A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1;14)(q21;q32) that forms a FCRL4-IGHA1 fusion protein. Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system. PTM:3-Hydroxykynurenine, an oxidized tryptophan metabolite that is common in biological fluids, reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352. Contains 3 Ig-like (immunoglobulin-like) domains. subunit:Monomeric or polymeric. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human IgA. AA range:227-276 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | IGHA1 antibody Ig alpha-1 chain C region antibody IGHA2 antibody Ig alpha-2 chain C region antibody |
|---|---|
| Molecular Weight(MW) | 38 kDa |
| Positive Control | Bile,Colon,Mammary gland,Stomach mucosa, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
