| Product Name | IL-10Rα |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IL10RA antibody; IL10R antibody; Interleukin-10 receptor subunit alpha antibody; IL-10 receptor subunit alpha antibody; IL-10R subunit alpha antibody; IL-10RA antibody; CDw210a antibody; Interleukin-10 receptor subunit 1 antibody; IL-10R subunit 1 antibody; IL-10R1 antibody; CD antigen CD210 antibody; |
| Product description | The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human IL-10R alpha. AA range:462-511 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIF |
| WB:1:500-1:2000 IF:1:100-1:500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | IL10RA antibody IL10R antibody Interleukin-10 receptor subunit alpha antibody IL-10 receptor subunit alpha antibody IL-10R subunit alpha antibody IL-10RA antibody CDw210a antibody Interleukin-10 receptor subunit 1 antibody IL-10R subunit 1 antibody IL-10R1 antibody CD antigen CD210 antibody |
|---|---|
| Molecular Weight(MW) | 63 kDa |
| SwissProt ID | Q13651 |
|---|
| Positive Control | Blood,Lymphoma,Spleen, |
|---|---|
| Application Notes | WB:1:500-1:2000 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
