| Product Name | IL-17RC |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IL17RC antibody; Interleukin-17 receptor C antibody; IL-17 receptor C antibody; IL-17RC antibody; Interleukin-17 receptor homolog antibody; IL17Rhom antibody; Interleukin-17 receptor-like protein antibody; IL-17RL antibody; ZcytoR14 antibody; |
| Product description | This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human IL17RC. AA range:721-770 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | IL17RC antibody Interleukin-17 receptor C antibody IL-17 receptor C antibody IL-17RC antibody Interleukin-17 receptor homolog antibody IL17Rhom antibody Interleukin-17 receptor-like protein antibody IL-17RL antibody ZcytoR14 antibody |
|---|---|
| Molecular Weight(MW) | 70 kDa |
| SwissProt ID | Q8NAC3 |
|---|
| Positive Control | Spleen,Uterus,Whole embryo, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
