| Product Name | ILT-3 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | LILRB4 antibody; ILT3 antibody; LIR5 antibody; Leukocyte immunoglobulin-like receptor subfamily B member 4 antibody; CD85 antigen-like family member K antibody; Immunoglobulin-like transcript 3 antibody; ILT-3 antibody; Leukocyte immunoglobulin-like receptor 5 antibody; LIR-5 antibody; Monocyte inhibitory receptor HM18 antibody; antibody; |
| Product description | This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13. 4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human LILRB4. AA range:201-250 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IF |
| IF:1:100-1:500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | LILRB4 antibody ILT3 antibody LIR5 antibody Leukocyte immunoglobulin-like receptor subfamily B member 4 antibody CD85 antigen-like family member K antibody Immunoglobulin-like transcript 3 antibody ILT-3 antibody Leukocyte immunoglobulin-like receptor 5 antibody LIR-5 antibody Monocyte inhibitory receptor HM18 antibody antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | Q8NHJ6 |
|---|
| Positive Control | Brain,Monocyte,Peripheral blood leukocyte,Placenta, |
|---|---|
| Application Notes | IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
