| Product Name | IRTKS |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BAIAP2L1 antibody; IRTKS antibody; Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 antibody; BAI1-associated protein 2-like protein 1 antibody; Insulin receptor tyrosine kinase substrate antibody; |
| Product description | This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal fo |
| Immunogen | The antiserum was produced against synthesized peptide derived from human BAIAP2L1. AA range:111-160 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | BAIAP2L1 antibody IRTKS antibody Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 antibody BAI1-associated protein 2-like protein 1 antibody Insulin receptor tyrosine kinase substrate antibody |
|---|---|
| Molecular Weight(MW) | 57 kDa |
| SwissProt ID | Q9UHR4 |
|---|
| Positive Control | Adrenal gland,Epithelium,Lung,Placenta, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
