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OM634876
Discount Price
OM634876-100ul
1~2 Week
100ul
OM634876-50ul
50ul
OM634876-20ul
20ul
1~2 Week
Product Profile
Product Name JIP-3
Antibody Type Primary Antibodies
Antigen Alias MAPK8IP3 antibody; JIP3 antibody; KIAA1066 antibody; C-Jun-amino-terminal kinase-interacting protein 3 antibody; JIP-3 antibody; JNK-interacting protein 3 antibody; JNK MAP kinase scaffold protein 3 antibody; Mitogen-activated protein kinase 8-interacting protein 3 antibody;
Product description The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Immunogen The antiserum was produced against synthesized peptide derived from human JIP3. AA range:621-670
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHCIF
WB:1:500-1:2000
IHC:1:100-1:300
IF:1:100-1:500
Species Reactivity HumanMouse
Concentration 1mg/ml
Target Information
Alternative Names MAPK8IP3 antibody
JIP3 antibody
KIAA1066 antibody
C-Jun-amino-terminal kinase-interacting protein 3 antibody
JIP-3 antibody
JNK-interacting protein 3 antibody
JNK MAP kinase scaffold protein 3 antibody
Mitogen-activated protein kinase 8-interacting protein 3 antibody
Molecular Weight(MW) 147 kDa
Database Links
SwissProt ID Q9UPT6
Positive Control Brain,Epithelium,Melanoma,Spleen,
Application Notes WB:1:500-1:2000
IHC:1:100-1:300
IF:1:100-1:500
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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