| Product Name | KCNQ2/3/4/5 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KCNQ2 antibody; Potassium voltage-gated channel subfamily KQT member 2 antibody; KQT-like 2 antibody; Neuroblastoma-specific potassium channel subunit alpha KvLQT2 antibody; Voltage-gated potassium channel subunit Kv7.2 antibody; KCNQ3 antibody; Potassium voltage-gated channel subfamily KQT me antibody; |
| Product description | The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Kv7.3/KCNQ3. AA range:191-240 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | KCNQ2 antibody Potassium voltage-gated channel subfamily KQT member 2 antibody KQT-like 2 antibody Neuroblastoma-specific potassium channel subunit alpha KvLQT2 antibody Voltage-gated potassium channel subunit Kv7.2 antibody KCNQ3 antibody Potassium voltage-gated channel subfamily KQT me antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| Positive Control | Brain,Eye,Fetal brain,Neuroblastoma,Temporal cortex |
|---|---|
| Application Notes | IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
