| Product Name | KCNQ4 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KCNQ4 antibody; Potassium voltage-gated channel subfamily KQT member 4 antibody; KQT-like 4 antibody; Potassium channel subunit alpha KvLQT4 antibody; Voltage-gated potassium channel subunit Kv7.4 antibody; |
| Product description | The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human KCNQ4. AA range:644-693 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | KCNQ4 antibody Potassium voltage-gated channel subfamily KQT member 4 antibody KQT-like 4 antibody Potassium channel subunit alpha KvLQT4 antibody Voltage-gated potassium channel subunit Kv7.4 antibody |
|---|---|
| Molecular Weight(MW) | 80 kDa |
| SwissProt ID | P56696 |
|---|
| Positive Control | Retina, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
