| Product Name | KDEL Receptor 2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KDELR2 antibody; ERD2.2 antibody; ER lumen protein retaining receptor 2 antibody; ERD2-like protein 1 antibody; ELP-1 antibody; KDEL endoplasmic reticulum protein retention receptor 2 antibody; KDEL receptor 2 antibody; |
| Product description | Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR2 was the second member of the family to be identified, and it encodes a protein which is 83% identical to the KDELR1 gene product. Alternative splicing r |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ERD22. AA range:81-130 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | KDELR2 antibody ERD2.2 antibody ER lumen protein retaining receptor 2 antibody ERD2-like protein 1 antibody ELP-1 antibody KDEL endoplasmic reticulum protein retention receptor 2 antibody KDEL receptor 2 antibody |
|---|---|
| Molecular Weight(MW) | 24 kDa |
| SwissProt ID | P33947 |
|---|
| Positive Control | Brain,Placenta,Skin,Testis,Uterus, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
