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OM634889
Discount Price
OM634889-100ul
1~2 Week
100ul
OM634889-50ul
50ul
OM634889-20ul
20ul
1~2 Week
Product Profile
Product Name KDEL Receptor 3
Antibody Type Primary Antibodies
Antigen Alias KDELR3 antibody; ER lumen protein retaining receptor 3 antibody; KDEL endoplasmic reticulum protein retention receptor 3 antibody; KDEL receptor 3 antibody;
Product description This gene encodes a member of the KDEL endoplasmic reticulum protein retention receptor family. Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR3 was the third member of the family to be identified. Alt
Immunogen The antiserum was produced against synthesized peptide derived from human ERD23. AA range:61-110
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:500-1:2000
IHC:1:100-1:300
Species Reactivity HumanMouse
Concentration 1mg/ml
Target Information
Alternative Names KDELR3 antibody
ER lumen protein retaining receptor 3 antibody
KDEL endoplasmic reticulum protein retention receptor 3 antibody
KDEL receptor 3 antibody
Molecular Weight(MW) 28 kDa
Database Links
SwissProt ID O43731
Positive Control Cervix,Kidney,Stomach,Synovial cell,
Application Notes WB:1:500-1:2000
IHC:1:100-1:300
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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