| Product Name | KOR-1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | OPRK1 antibody; OPRK antibody; Kappa-type opioid receptor antibody; K-OR-1 antibody; KOR-1 antibody; |
| Product description | OPRK1 encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. |
| Immunogen | The antiserum was produced against synthesized peptide derived from mouse KOR-1. AA range:331-380 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | MouseRat |
| Concentration | 1mg/ml |
| Alternative Names | OPRK1 antibody OPRK antibody Kappa-type opioid receptor antibody K-OR-1 antibody KOR-1 antibody |
|---|---|
| Molecular Weight(MW) | 42 kDa |
| SwissProt ID | P33534 |
|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
