| Product Name |
Kpm |
| Antibody Type |
Primary Antibodies |
| Antigen Alias |
LATS2 antibody; KPM antibody; Serine/threonine-protein kinase LATS2 antibody; Kinase phosphorylated during mitosis protein antibody; Large tumor suppressor homolog 2 antibody; Serine/threonine-protein kinase kpm antibody; Warts-like kinase antibody; |
| Product description |
This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. |
| Immunogen |
The antiserum was produced against synthesized peptide derived from human LATS2. AA range:541-590 |