| Product Name | Ksr2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KSR2 antibody; Kinase suppressor of Ras 2 antibody; hKSR2 antibody; |
| Product description | domain:The protein kinase domain is predicted to be catalytically inactive. Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production. PTM:Phosphorylated on Ser-474 by MARK3. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Contains 1 phorbol-ester/DAG-type zinc finger. Contains 1 protein kinase domain. subunit:Interacts with MAP2K1, MAP3K8, MAPK, RAS and RAF. tissue specificity:Mainly expressed in brain and kidney. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human KSR2. AA range:671-720 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | KSR2 antibody Kinase suppressor of Ras 2 antibody hKSR2 antibody |
|---|---|
| Molecular Weight(MW) | 108 kDa |
| SwissProt ID | Q6VAB6 |
|---|
| Positive Control | Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
