domain:The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position. Potassium channel subunit. Modulates channel activity and reduces the ion flow. Belongs to the potassium channel family. S subfamily. subcellular location:May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1. subunit:Heteromultimer with KCNB1 and with KCNB2. Does not form homomultimers. Might also bind to other channel proteins.
Immunogen
The antiserum was produced against synthesized peptide derived from human KCNS2. AA range:197-246