| Product Name | LAT |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | LAT antibody; Linker for activation of T-cells family member 1 antibody; 36 kDa phospho-tyrosine adapter protein antibody; pp36 antibody; p36-38 antibody; |
| Product description | The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human LAT. AA range:171-220 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | LAT antibody Linker for activation of T-cells family member 1 antibody 36 kDa phospho-tyrosine adapter protein antibody pp36 antibody p36-38 antibody |
|---|---|
| Molecular Weight(MW) | 38 kDa |
| SwissProt ID | O43561 |
|---|
| Positive Control | Colon,Leukemia,Platelet,Thymus, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
