| Product Name | Latrophilin-1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | LPHN1 antibody; KIAA0821 antibody; LEC2 antibody; Latrophilin-1 antibody; Calcium-independent alpha-latrotoxin receptor 1 antibody; CIRL-1 antibody; Lectomedin-2 antibody; |
| Product description | This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms., |
| Immunogen | The antiserum was produced against synthesized peptide derived from human LPHN1. AA range:561-610 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IF |
| IF:1:100-1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | LPHN1 antibody KIAA0821 antibody LEC2 antibody Latrophilin-1 antibody Calcium-independent alpha-latrotoxin receptor 1 antibody CIRL-1 antibody Lectomedin-2 antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | O94910 |
|---|
| Positive Control | Brain,Lung,T-cell,Whole embryo, |
|---|---|
| Application Notes | IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
