| Product Name | Lck |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | LCK antibody; Tyrosine-protein kinase Lck antibody; Leukocyte C-terminal Src kinase antibody; LSK antibody; Lymphocyte cell-specific protein-tyrosine kinase antibody; Protein YT16 antibody; Proto-oncogene Lck antibody; T cell-specific protein-tyrosine kinase antibody; p56-LCK antibody; |
| Product description | This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Lck. AA range:161-210 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | LCK antibody Tyrosine-protein kinase Lck antibody Leukocyte C-terminal Src kinase antibody LSK antibody Lymphocyte cell-specific protein-tyrosine kinase antibody Protein YT16 antibody Proto-oncogene Lck antibody T cell-specific protein-tyrosine kinase antibody p56-LCK antibody |
|---|---|
| Molecular Weight(MW) | 56 kDa |
| SwissProt ID | P06239 |
|---|
| Positive Control | Blood,Leukemia,Leukemic T-cell,Lymph,Mammary cancer,Periphe |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
