| Product Name | LEKTI |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SPINK5 antibody; Serine protease inhibitor Kazal-type 5 antibody; Lympho-epithelial Kazal-type-related inhibitor antibody; LEKTI antibody; |
| Product description | This gene encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The encoded preproprotein is proteolytically processed to generate multiple protein products, which may exhibit unique activities and specificities. These proteins may play a role in skin and hair morphogenesis, as well as anti-inflammatory and antimicrobial protection of mucous epithelia. Mutations in this gene may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy. This gene is present in a gene cluster on chromosome 5. Alternative splicing results in multiple transcript variants. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SPINK5. AA range:494-543 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SPINK5 antibody Serine protease inhibitor Kazal-type 5 antibody Lympho-epithelial Kazal-type-related inhibitor antibody LEKTI antibody |
|---|---|
| Molecular Weight(MW) | 120 kDa |
| SwissProt ID | Q9NQ38 |
|---|
| Positive Control | Epithelium,Foreskin keratinocyte, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
