| Product Name |
Mad 4 |
| Antibody Type |
Primary Antibodies |
| Antigen Alias |
MXD4 antibody; BHLHC12 antibody; MAD4 antibody; Max dimerization protein 4 antibody; Max dimerizer 4 antibody; Class C basic helix-loop-helix protein 12 antibody; bHLHc12 antibody; Max-associated protein 4 antibody; Max-interacting transcriptional repressor MAD4 antibody; |
| Product description |
This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. |
| Immunogen |
The antiserum was produced against synthesized peptide derived from human MAD4. AA range:10-59 |