| Product Name | MADD |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MADD antibody; DENN antibody; IG20 antibody; KIAA0358 antibody; MAP kinase-activating death domain protein antibody; Differentially expressed in normal and neoplastic cells antibody; Insulinoma glucagonoma clone 20 antibody; Rab3 GDP/GTP exchange factor antibody; |
| Product description | Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MADD. AA range:751-800 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | MADD antibody DENN antibody IG20 antibody KIAA0358 antibody MAP kinase-activating death domain protein antibody Differentially expressed in normal and neoplastic cells antibody Insulinoma glucagonoma clone 20 antibody Rab3 GDP/GTP exchange factor antibody |
|---|---|
| Molecular Weight(MW) | 183 kDa |
| SwissProt ID | Q8WXG6 |
|---|
| Positive Control | Brain,Fetal liver,Insulinoma,Liver,Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
