| Product Name | MAN1B1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MAN1B1 antibody; Endoplasmic reticulum mannosyl-oligosaccharide 1 antibody; 2-alpha-mannosidase antibody; ER alpha-1,2-mannosidase antibody; ER mannosidase 1 antibody; ERMan1 antibody; Man9GlcNAc2-specific-processing alpha-mannosidase antibody; Mannosidase alpha class 1B member 1 antibody; |
| Product description | This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. |
| Immunogen | Synthesized peptide derived from MAN1B1 . at AA range: 100-180 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | MAN1B1 antibody Endoplasmic reticulum mannosyl-oligosaccharide 1 antibody 2-alpha-mannosidase antibody ER alpha-1 2-mannosidase antibody ER mannosidase 1 antibody ERMan1 antibody Man9GlcNAc2-specific-processing alpha-mannosidase antibody Mannosidase alpha class 1B member 1 antibody |
|---|---|
| Molecular Weight(MW) | 80 kDa |
| SwissProt ID | Q9UKM7 |
|---|
| Positive Control | Brain,Fetal brain,Liver,Lung,Placenta,Testis,Uterus,Whole embryo, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
