| Product Name | Manic Fringe |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MFNG antibody; Beta-1 antibody; 3-N-acetylglucosaminyltransferase manic fringe antibody; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase antibody; |
| Product description | This gene is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MFNG. AA range:61-110 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | MFNG antibody Beta-1 antibody 3-N-acetylglucosaminyltransferase manic fringe antibody O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase antibody |
|---|---|
| Molecular Weight(MW) | 38 kDa |
| SwissProt ID | O00587 |
|---|
| Positive Control | Lymph, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
