| Product Name | MARCH1 Polyclonal Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MARCH1 antibody; RNF171 antibody; E3 ubiquitin-protein ligase MARCH1 antibody; Membrane-associated RING finger protein 1 antibody; Membrane-associated RING-CH protein I antibody; MARCH-I antibody; RING finger protein 171 antibody; |
| Product description | MARCH1 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6. 3. 2. 19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal compartment (Bartee et al. 2004 |
| Immunogen | Synthesized peptide derived from the Internal region of human 40603. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | MARCH1 antibody RNF171 antibody E3 ubiquitin-protein ligase MARCH1 antibody Membrane-associated RING finger protein 1 antibody Membrane-associated RING-CH protein I antibody MARCH-I antibody RING finger protein 171 antibody |
|---|---|
| Molecular Weight(MW) | 32 kDa |
| SwissProt ID | Q8TCQ1 |
|---|
| Positive Control | Brain,Ileal mucosa, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
