| Product Name | MCM4 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MCM4 antibody; CDC21 antibody; DNA replication licensing factor MCM4 antibody; CDC21 homolog antibody; P1-CDC21 antibody; |
| Product description | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcri |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MCM4. AA range:20-69 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | MCM4 antibody CDC21 antibody DNA replication licensing factor MCM4 antibody CDC21 homolog antibody P1-CDC21 antibody |
|---|---|
| Molecular Weight(MW) | 96 kDa |
| SwissProt ID | P33991 |
|---|
| Positive Control | Cervix,Epithelium,Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
