| Product Name | Midline-1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MID1 antibody; FXY antibody; RNF59 antibody; TRIM18 antibody; XPRF antibody; Midline-1 antibody; Midin antibody; Midline 1 RING finger protein antibody; Putative transcription factor XPRF antibody; RING finger protein 59 antibody; Tripartite motif-containing protein 18 antibody; |
| Product description | The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Multiple different transcript variants are generated by alternate splicing; however, t |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TRI18. AA range:71-120 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | MID1 antibody FXY antibody RNF59 antibody TRIM18 antibody XPRF antibody Midline-1 antibody Midin antibody Midline 1 RING finger protein antibody Putative transcription factor XPRF antibody RING finger protein 59 antibody Tripartite motif-containing protein 18 antibody |
|---|---|
| Molecular Weight(MW) | 75 kDa |
| SwissProt ID | O15344 |
|---|
| Positive Control | Brain,Epithelium,Fetal kidney,Neuron,Placenta,Skin, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
