| Product Name | MKP-4 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DUSP9 antibody; MKP4 antibody; Dual specificity protein phosphatase 9 antibody; Mitogen-activated protein kinase phosphatase 4 antibody; MAP kinase phosphatase 4 antibody; MKP-4 antibody; |
| Product description | The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases and is localized to the cytoplasm and nucleus. Aberrant expression of this gene is associated with type 2 diabetes and cancer progr |
| Immunogen | The antiserum was produced against synthesized peptide derived from human DUSP9. AA range:151-200 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | DUSP9 antibody MKP4 antibody Dual specificity protein phosphatase 9 antibody Mitogen-activated protein kinase phosphatase 4 antibody MAP kinase phosphatase 4 antibody MKP-4 antibody |
|---|---|
| Molecular Weight(MW) | 42 kDa |
| SwissProt ID | Q99956 |
|---|
| Positive Control | Kidney,Liver,Lung,Placenta, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
