| Product Name | MLH3 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MLH3 antibody; DNA mismatch repair protein Mlh3 antibody; MutL protein homolog 3 antibody; |
| Product description | This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MLH3. AA range:521-570 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | MLH3 antibody DNA mismatch repair protein Mlh3 antibody MutL protein homolog 3 antibody |
|---|---|
| Molecular Weight(MW) | 164 kDa |
| SwissProt ID | Q9UHC1 |
|---|
| Positive Control | Brain,Cerebellum,Melanoma, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
