| Product Name |
MLK1/2 |
| Antibody Type |
Primary Antibodies |
| Antigen Alias |
MAP3K9 antibody; MLK1 antibody; PRKE1 antibody; Mitogen-activated protein kinase kinase kinase 9 antibody; Mixed lineage kinase 1 antibody; MAP3K10 antibody; MLK2 antibody; MST antibody; Mitogen-activated protein kinase kinase kinase 10 antibody; Mixed lineage kinase 2 antibody; Protein kinase MST antibody; |
| Product description |
catalytic activity:ATP + a protein = ADP + a phosphoprotein. cofactor:Magnesium. enzyme regulation:Homodimerization via the leucine zipper domains is required for autophosphorylation and subsequent activation. Activates the JUN N-terminal pathway. PTM:Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation. Thr-312 is likely to be the main autophosphorylation site. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. Contains 1 protein kinase domain. Contains 1 SH3 domain. subunit:Homodimer. tissue specificity:Expressed in epithelial tumor cell lines of colonic, breast and esophageal origin. |
| Immunogen |
The antiserum was produced against synthesized peptide derived from human MLK1/2. AA range:281-330 |