| Product Name | MLK3 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MAP3K11 antibody; MLK3 antibody; PTK1 antibody; SPRK antibody; Mitogen-activated protein kinase kinase kinase 11 antibody; Mixed lineage kinase 3 antibody; Src-homology 3 domain-containing proline-rich kinase antibody; |
| Product description | The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MLK3. AA range:640-689 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | MAP3K11 antibody MLK3 antibody PTK1 antibody SPRK antibody Mitogen-activated protein kinase kinase kinase 11 antibody Mixed lineage kinase 3 antibody Src-homology 3 domain-containing proline-rich kinase antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | Q16584 |
|---|
| Positive Control | Brain,Epithelium,Hippocampus,Liver,Megakaryocyte,Sp |
|---|---|
| Application Notes | IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
