| Product Name |
MRGX1 |
| Antibody Type |
Primary Antibodies |
| Antigen Alias |
MRGPRX1 antibody; MRGX1 antibody; SNSR3 antibody; SNSR4 antibody; Mas-related G-protein coupled receptor member X1 antibody; Sensory neuron-specific G-protein coupled receptor 3/4 antibody; |
| Product description |
Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Belongs to the G-protein coupled receptor 1 family. Mas subfamily. tissue specificity:Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. |
| Immunogen |
The antiserum was produced against synthesized peptide derived from human MRGX1. AA range:271-320 |