| Product Name | M-RIP |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MPRIP antibody; KIAA0864 antibody; MRIP antibody; RHOIP3 antibody; Myosin phosphatase Rho-interacting protein antibody; M-RIP antibody; Rho-interacting protein 3 antibody; RIP3 antibody; p116Rip antibody; |
| Product description | Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells. Contains 1 PH domain. Contains 2 PH domains. subcellular location:Colocalizes with F-actin. subunit:Binds F-actin through its N-terminus (By similarity). Binds RHOA, PPP1R12A/MBS and PPP1R12C/MBS85 through adjacent coiled coil domains. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MPRIP. AA range:723-772 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | MPRIP antibody KIAA0864 antibody MRIP antibody RHOIP3 antibody Myosin phosphatase Rho-interacting protein antibody M-RIP antibody Rho-interacting protein 3 antibody RIP3 antibody p116Rip antibody |
|---|---|
| Molecular Weight(MW) | 110 kDa |
| SwissProt ID | Q6WCQ1 |
|---|
| Positive Control | Aorta,Brain,Epithelium,Lymph,Melanoma,Muscle,Ovary,Tongue, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
