| Product Name | MRTF-A |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MKL1 antibody; KIAA1438 antibody; MAL antibody; MKL/myocardin-like protein 1 antibody; Megakaryoblastic leukemia 1 protein antibody; Megakaryocytic acute leukemia protein antibody; Myocardin-related transcription factor A antibody; MRTF-A antibody; |
| Product description | The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MKL1. AA range:10-59 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | MKL1 antibody KIAA1438 antibody MAL antibody MKL/myocardin-like protein 1 antibody Megakaryoblastic leukemia 1 protein antibody Megakaryocytic acute leukemia protein antibody Myocardin-related transcription factor A antibody MRTF-A antibody |
|---|---|
| Molecular Weight(MW) | 99 kDa |
| SwissProt ID | Q969V6 |
|---|
| Positive Control | Blood,Brain,Epithelium,PCR rescued clones,Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
