| Product Name | MSH3 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MSH3 antibody; DUC1 antibody; DUG antibody; DNA mismatch repair protein Msh3 antibody; hMSH3 antibody; Divergent upstream protein antibody; DUP antibody; Mismatch repair protein 1 antibody; MRP1 antibody; |
| Product description | The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MSH3. AA range:51-100 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | MSH3 antibody DUC1 antibody DUG antibody DNA mismatch repair protein Msh3 antibody hMSH3 antibody Divergent upstream protein antibody DUP antibody Mismatch repair protein 1 antibody MRP1 antibody |
|---|---|
| Molecular Weight(MW) | 127 kDa |
| SwissProt ID | P20585 |
|---|
| Positive Control | Muscle, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
