| Product Name | Sin3B |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SIN3B antibody; KIAA0700 antibody; Paired amphipathic helix protein Sin3b antibody; Histone deacetylase complex subunit Sin3b antibody; Transcriptional corepressor Sin3b antibody; |
| Product description | Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. Contains 3 PAH (paired amphipathic helix) repeats. subunit:Interacts with FOXK1/MNF, MXI, MAD, NCOR1 and SAP30. Interaction with SDS3 enhances the interaction with HDAC1 to form a complex. Interacts with MAD3, MAD4, MAEL, REST and SETDB1 (By similarity). Interacts with HCFC1. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SIN3B. AA range:221-270 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIF |
| WB:1:500-1:2000 IF:1:100-1:500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SIN3B antibody KIAA0700 antibody Paired amphipathic helix protein Sin3b antibody Histone deacetylase complex subunit Sin3b antibody Transcriptional corepressor Sin3b antibody |
|---|---|
| Molecular Weight(MW) | 130 kDa |
| SwissProt ID | O75182 |
|---|
| Positive Control | Brain,Duodenum,Lung,Skin, |
|---|---|
| Application Notes | WB:1:500-1:2000 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
