| Product Name | Myomesin-1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MYOM1 antibody; Myomesin-1 antibody; 190 kDa connectin-associated protein antibody; 190 kDa titin-associated protein antibody; Myomesin family member 1 antibody; |
| Product description | The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD (myomesin 1) and 165 kD (myomesin 2). This protein, myomesin 1, like myomesin 2, titin, and other myofibrillar proteins contains structural modules with strong homology to either fibronectin type III (motif I) or immunoglobulin C2 (motif II) domains. Myomesin 1 and myomesin 2 each have a unique N-terminal region followed by 12 modules of motif I or motif II, in the arrangement II-II-I-I-I-I-I-II-II-II-II-II. The two proteins share 50% sequence identity in this repeat-containing region. The head structure formed by these 2 proteins on one end of the titin string extends into the center of the M band. The integrating structure |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MYOM1. AA range:824-873 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | MYOM1 antibody Myomesin-1 antibody 190 kDa connectin-associated protein antibody 190 kDa titin-associated protein antibody Myomesin family member 1 antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | P52179 |
|---|
| Positive Control | Heart muscle,Skeletal muscle, |
|---|---|
| Application Notes | IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
