| Product Name | MYPT3 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PPP1R16A antibody; MYPT3 antibody; Protein phosphatase 1 regulatory subunit 16A antibody; Myosin phosphatase-targeting subunit 3 antibody; |
| Product description | Myosin light chain kinase and phosphatase (MLCP) complexes control the phosphorylation states of regulatory myosin light chains, which is crucial for muscle and intracellular movement. MLCPs typically contain a catalytic protein phosphatase 1 (PP1c) subunit, a myosin phosphatase targeting (MYPT) subunit, and another smaller subunit. The protein encoded by this gene represents an MYPT subunit, which is responsible for directing PP1c to its intended targets. However, while other MYPTs result in PP1c activation after becoming phosphorylated, the encoded protein is phosphorylated by protein kinase A and then inhibits the catalytic activity of PP1c. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PPP1R16A. AA range:362-411 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | PPP1R16A antibody MYPT3 antibody Protein phosphatase 1 regulatory subunit 16A antibody Myosin phosphatase-targeting subunit 3 antibody |
|---|---|
| Molecular Weight(MW) | 60 kDa |
| SwissProt ID | Q96I34 |
|---|
| Positive Control | Lung,Placenta,Spleen,Uterus, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
