| Product Name | N/H/K-Ras |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NRAS antibody; HRAS1 antibody; GTPase NRas antibody; Transforming protein N-Ras antibody; HRAS antibody; HRAS1 antibody; GTPase HRas antibody; H-Ras-1 antibody; Ha-Ras antibody; Transforming protein p21 antibody; c-H-ras antibody; p21ras antibody; KRAS antibody; KRAS2 antibody; RASK2 antibody; GTPase KRas antibody; K-Ras 2 antibody; Ki-Ras antibody; c-K-ras antibody; c-Ki-ras antibody; |
| Product description | This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RASH/RASK. AA range:1-50 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | NRAS antibody HRAS1 antibody GTPase NRas antibody Transforming protein N-Ras antibody HRAS antibody HRAS1 antibody GTPase HRas antibody H-Ras-1 antibody Ha-Ras antibody Transforming protein p21 antibody c-H-ras antibody p21ras antibody KRAS antibody KRAS2 antibody RASK2 antibody GTPase KRas antibody K-Ras 2 antibody Ki-Ras antibody c-K-ras antibody c-Ki-ras antibody |
|---|---|
| Molecular Weight(MW) | 21 kDa |
| Positive Control | Bone marrow,Bone-marrow,Brain,Fibrosarcoma,Kidney,Leukemia,Lung car |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
