| Product Name | NARF |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NARF antibody; Nuclear prelamin A recognition factor antibody; Iron-only hydrogenase-like protein 2 antibody; IOP2 antibody; |
| Product description | Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein-protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif. This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A. The protein encoded by this gene binds to the prenylated prelamin A carboxyl-terminal tail domain. It may be a component of a prelamin A endoprotease complex. The encoded protein is located in the nucleus, where it partially colocalizes with the nuclear lamina. It |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NARF. AA range:262-311 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | NARF antibody Nuclear prelamin A recognition factor antibody Iron-only hydrogenase-like protein 2 antibody IOP2 antibody |
|---|---|
| Molecular Weight(MW) | 51 kDa |
| SwissProt ID | Q9UHQ1 |
|---|
| Positive Control | Embryo,Lung,Placenta,Skeletal muscle, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
