| Product Name | NDR2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | catalytic activity:ATP + a protein = ADP + a phosphoprotein. cofactor:Magnesium. enzyme regulation:Activated by binding of S100B which releases autoinhibitory N-lobe interactions, enabling ATP to bind and the autophosphorylation of Ser-282. Thr-442 then undergoes calcium-dependent phosphorylation by an upstream kinase. Interactions between phosphorylated Thr-442 and the N-lobe promote additional structural changes that complete the activation of the kinase. Autoinhibition is also released by the binding of MOB1/MOBKL1A and MOB2/HCCA2 to the N-terminal of STK38L. Involved in the regulation of structural processes in differentiating and mature neuronal cells. PTM:Phosphorylated upon DNA damage, probably by ATM or ATR. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. Contains 1 AGC-kinase C-terminal domain. Contains 1 protein kinase domain. subcellular location:Associated with the actin cytoskeleton. subunit:Homodimeric S100B binds two molecules of STK38L (By similarity). Interacts with MOB1 and MOB2. tissue specificity:Ubiquitously expressed with highest levels observed in the thymus. |
| Immunogen | Synthesized peptide derived from NDR2 . at AA range: 380-460 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:1:500-1:2000 IHC:1:50-300: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | STK38L antibody KIAA0965 antibody NDR2 antibody Serine/threonine-protein kinase 38-like antibody NDR2 protein kinase antibody Nuclear Dbf2-related kinase 2 antibody |
|---|---|
| Molecular Weight(MW) | 54 kDa |
| SwissProt ID | Q9Y2H1 |
|---|
| Positive Control | Brain,Cervix carcinoma,Lung carcinoma,Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:50-300: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
