| Product Name | Nephrocystin-5 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IQCB1 antibody; KIAA0036 antibody; NPHP5 antibody; OK/SW-cl.85 antibody; IQ calmodulin-binding motif-containing protein 1 antibody; Nephrocystin-5 antibody; p53 and DNA damage-regulated IQ motif protein antibody; PIQ antibody; |
| Product description | This gene encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. The encoded protein has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. The protein is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5. Alternative splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human IQCB1. AA range:431-480 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | IQCB1 antibody KIAA0036 antibody NPHP5 antibody OK/SW-cl.85 antibody IQ calmodulin-binding motif-containing protein 1 antibody Nephrocystin-5 antibody p53 and DNA damage-regulated IQ motif protein antibody PIQ antibody |
|---|---|
| Molecular Weight(MW) | 69 kDa |
| SwissProt ID | Q15051 |
|---|
| Positive Control | Bone marrow,Colon adenocarcinoma,Ovary, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
