| Product Name | Neurexin I |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NRXN1 antibody; KIAA0578 antibody; Neurexin-1-alpha antibody; Neurexin I-alpha antibody; |
| Product description | NRXN1 (neurexin 1) encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca(2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for NRXN1 in the 3' region. Mutations in NRXN1 are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NRXN1. AA range:502-551 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | NRXN1 antibody KIAA0578 antibody Neurexin-1-alpha antibody Neurexin I-alpha antibody |
|---|---|
| Molecular Weight(MW) | 150 kDa |
| SwissProt ID | Q9ULB1 |
|---|
| Application Notes | WB:1:500-1:2000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
