| Product Name | Neurofibromin |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NF1 antibody; Neurofibromin antibody; Neurofibromatosis-related protein NF-1 antibody; |
| Product description | This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NF1. AA range:1551-1600 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIF |
| WB:1:500-1:2000 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | NF1 antibody Neurofibromin antibody Neurofibromatosis-related protein NF-1 antibody |
|---|---|
| Molecular Weight(MW) | 319 kDa |
| SwissProt ID | P21359 |
|---|
| Positive Control | Brain,Epithelium,Human retina,Kidney, |
|---|---|
| Application Notes | WB:1:500-1:2000 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
