| Product Name | OCTN2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SLC22A5 antibody; OCTN2 antibody; Solute carrier family 22 member 5 antibody; High-affinity sodium-dependent carnitine cotransporter antibody; Organic cation/carnitine transporter 2 antibody; |
| Product description | Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. Alternative splicing of this gene results in multiple transcript variants. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SLC22A5. AA range:300-349 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SLC22A5 antibody OCTN2 antibody Solute carrier family 22 member 5 antibody High-affinity sodium-dependent carnitine cotransporter antibody Organic cation/carnitine transporter 2 antibody |
|---|---|
| Molecular Weight(MW) | 65 kDa |
| SwissProt ID | O76082 |
|---|
| Positive Control | Brain,Kidney,Lung,Trachea, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
