| Product Name | p107 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RBL1 antibody; Retinoblastoma-like protein 1 antibody; 107 kDa retinoblastoma-associated protein antibody; p107 antibody; pRb1 antibody; |
| Product description | The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms hav |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RBL1. AA range:335-384 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IF |
| IF:1:100-1:500 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | RBL1 antibody Retinoblastoma-like protein 1 antibody 107 kDa retinoblastoma-associated protein antibody p107 antibody pRb1 antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | P28749 |
|---|
| Positive Control | Testis, |
|---|---|
| Application Notes | IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
