| Product Name | p18 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CDKN2C antibody; CDKN6 antibody; Cyclin-dependent kinase 4 inhibitor C antibody; Cyclin-dependent kinase 6 inhibitor antibody; p18-INK4c antibody; p18-INK6 antibody; |
| Product description | The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human p18 INK. AA range:111-160 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseMonkey |
| Concentration | 1mg/ml |
| Alternative Names | CDKN2C antibody CDKN6 antibody Cyclin-dependent kinase 4 inhibitor C antibody Cyclin-dependent kinase 6 inhibitor antibody p18-INK4c antibody p18-INK6 antibody |
|---|---|
| Molecular Weight(MW) | 18 kDa |
| SwissProt ID | P42773 |
|---|
| Positive Control | Brain,Kidney,Mammary gland,Tongue,Uterus, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
