| Product Name | p53RFP |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RNF144B antibody; IBRDC2 antibody; P53RFP antibody; E3 ubiquitin-protein ligase RNF144B antibody; IBR domain-containing protein 2 antibody; RING finger protein 144B antibody; p53-inducible RING finger protein antibody; |
| Product description | caution:Lacks the His residue in the RING-type domain 2 that is one of the conserved features of the family. domain:The RING-type zinc finger domain mediates binding to an E2 ubiquitin-conjugating enzyme. E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a TP53/p53-dependent but caspase-independent mechanism. pathway:Protein modification; protein ubiquitination. PTM:Auto-ubiquitinated. Belongs to the RBR family. RNF144 subfamily. Contains 1 IBR-type zinc finger. Contains 2 RING-type zinc fingers. subunit:Interacts with UBE2L3, UBE2L6 and LCMT2. tissue specificity:Broadly expressed, with lowest levels in brain, spleen and thymus. |
| Immunogen | Synthesized peptide derived from the Internal region of human p53RFP. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | RNF144B antibody IBRDC2 antibody P53RFP antibody E3 ubiquitin-protein ligase RNF144B antibody IBR domain-containing protein 2 antibody RING finger protein 144B antibody p53-inducible RING finger protein antibody |
|---|---|
| Molecular Weight(MW) | 35 kDa |
| SwissProt ID | Q7Z419 |
|---|
| Positive Control | Placenta,Skeletal muscle, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
