| Product Name | PAK4/5/6 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PAK4 antibody; KIAA1142 antibody; Serine/threonine-protein kinase PAK 4 antibody; p21-activated kinase 4 antibody; PAK-4 antibody; |
| Product description | PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PAK4/5/6. AA range:441-490 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | PAK4 antibody KIAA1142 antibody Serine/threonine-protein kinase PAK 4 antibody p21-activated kinase 4 antibody PAK-4 antibody |
|---|---|
| Molecular Weight(MW) | 80 kDa |
| SwissProt ID | O96013 |
|---|
| Positive Control | Brain,Epithelium,Eye,Lymphoma,Neuroblastoma,Pancreas,Placenta,Teratocarcino |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
